Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents

Authors

DOI:

https://doi.org/10.9771/cp.v16i6.51754

Keywords:

Labdanes, Patents, Anticancer.

Abstract

Labdanes diterpenes are important natural products and express several pharmacological activities of interest, such as anticancer activity. In this sense, this work examined the innovation potential of labdane-type diterpenes as anticancer agents. For this purpose, a patent search was performed in the databases INP1, EPO, WIPO, Derwent Innovations Index, and Lens Patents using “labdane and cancer” as keywords. The results revealed 28 documents considered eligible, distributed among different international patent platforms, with registrations mainly carried out by China (36%), considering the period from 1984 to 2021. These patents are concentrated in A61 (65.06%) and C07 (34.26%) type categories, according to CIP classification. Thus, it can be inferred that there is little innovative activity for use of labdanes as anticancer agents globally, no activity registered in Brazil, and a majority patent classification for biological and chemical applications, which suggests a window of opportunity in this field of innovation.

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Author Biographies

Jailton de Souza-Ferrari, Federal University of Paraíba

PhD in Organic Chemistry from the Federal University of Bahia in 2007.

Wellyson Cavalcante de Oliveira, Federal University of Paraíba

Degree in Chemistry and Bachelor in Chemistry from the Federal University of Paraíba, Campus I, João Pessoa - PB.

Bruna Braga Dantas , Federal University of Campina Grande

Graduated in Nursing, Master in Natural and Synthetic Bioactive Products and PhD in Biotechnology from the Federal University of Paraíba, Campus I, João Pessoa - PB.

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Published

2023-10-01

How to Cite

Souza-Ferrari, J. de, Oliveira, W. C. de ., & Dantas , B. B. (2023). Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents. Cadernos De Prospecção, 16(6), 1987–2002. https://doi.org/10.9771/cp.v16i6.51754

Issue

Vol. 16 No. 6 (2023)

Section

Prospecções Tecnológicas de Assuntos Específicos

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