Technologic Prospection of Labdane-Type Diterpenes and their Derivatives as Anticancer Agents
DOI:
https://doi.org/10.9771/cp.v16i6.51754Keywords:
Labdanes, Patents, Anticancer.Abstract
Labdanes diterpenes are important natural products and express several pharmacological activities of interest, such as anticancer activity. In this sense, this work examined the innovation potential of labdane-type diterpenes as anticancer agents. For this purpose, a patent search was performed in the databases INP1, EPO, WIPO, Derwent Innovations Index, and Lens Patents using “labdane and cancer” as keywords. The results revealed 28 documents considered eligible, distributed among different international patent platforms, with registrations mainly carried out by China (36%), considering the period from 1984 to 2021. These patents are concentrated in A61 (65.06%) and C07 (34.26%) type categories, according to CIP classification. Thus, it can be inferred that there is little innovative activity for use of labdanes as anticancer agents globally, no activity registered in Brazil, and a majority patent classification for biological and chemical applications, which suggests a window of opportunity in this field of innovation.
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