Potencialidades Farmacológicas da Espécie Vinagreira: um estudo realizado por meio das técnicas de prospecção científica e tecnológica

Authors

  • Katiury Castro Cavalcante Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil
  • Gladson Diniz Pinheiro Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil
  • Álvaro Itaúna Schalcher Pereira Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil https://orcid.org/0000-0001-5415-9701
  • Oswaldo Palma Lopes Sobrinho Federal Institute of Education, Science and Technology of Goiás, Campus Rio Verde, Goiás, GO, Brazil https://orcid.org/0000-0002-4632-695X
  • Layane Bastos dos Santos Federal Institute of Education, Science and Technology of Maranhão, MA, Brazil
  • Francisco Adelton Alves Ribeiro Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil

DOI:

https://doi.org/10.9771/cp.v12i4.32490

Keywords:

Hibisco, Compostos químicos, Patente.

Abstract

Este artigo descreve utilizando técnicas de prospecção científica e tecnológica informações sobre a hortaliça da espécie Hibiscus sabdariffa L. presentes nos bancos de dados nacionais e internacionais avaliando seus aspectos químicos e aplicações farmacológicas/medicinais. Para isso, foram realizadas buscas nas bases de dado científicas Web of Science e Scopus e nos bancos de patentes: Instituto Nacional da Propriedade Industrial (INPI) e World Intellectual Property Organization (WIPO). Das bases estudadas, a Scopus e WIPO foram as que obtiveram mais resultados em número de publicações e patentes depositadas. A Nigéria foi o país que mais publicou sobre o hibisco no período de 2007-2017, seguida da Índia e Taiwan. A China foi o país com maior número de patentes registradas, detendo 53% dos resultados. O Brasil apresentou uma baixa proporção no número de depósitos. Os documentos encontrados na WIPO se enquadraram nas seções A e C da classificação CIP, com a maioria deles inclusos na subclasse A61K (preparações para finalidades médicas, odontológicas ou higiênicas).

Downloads

Download data is not yet available.

Author Biographies

Katiury Castro Cavalcante, Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil

Degree in Chemistry from the Federal Institute of Education, Science and Technology of Maranhão (IFMA).

Gladson Diniz Pinheiro, Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil

Degree in Chemistry from the Federal Institute of Education, Science and Technology of Maranhão (IFMA).

Álvaro Itaúna Schalcher Pereira, Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil

Doctor in Food Science and Engineering from the Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), MBA in Science, Technology and Innovation Teaching Management from Faculdade Integrada Metropolitana de Campinas (IBTA), Master in Chemistry, Specialist in Informatics in Education and Graduated in Full Licentiate in Chemistry, all from the Federal University of Maranhão (UFMA) . Professor of Basic, Technical and Technological Education (EBTT) at the Federal Institute of Education, Science and Technology of Maranhão (IFMA). Ad Hoc Consultant (FAPEMA/PATRONAGE). Advisor, Co-advisor and Member of Scientific Initiation and Research Projects (PIBIC), of the Institutional Scholarship Program for Initiation in Technological Development and Innovation (PIBITI) for Higher and Secondary Education, in addition to Coordination in Institutional Project. Leader of the Research Group registered at the National Council for Scientific and Technological Development (CNPq) in Food, Chemistry, Agronomy and Water Resources (AQARH) and Member of the Research Groups: Chemistry, Environment and Science Teaching (QMAEC); Autonomous Nucleus for Sustainable Actions in Analytical Chemistry, Food and Water (NASQA). It is part of the Knowledge and Competence Recognition Appraiser Bank (RSC) and the Appraiser Board of the Scientific Committee in the field of Agricultural Sciences of the Federal Institute of Education, Science and Technology of Maranhão (IFMA). He has experience in the areas of Exact and Earth Sciences, Agricultural Sciences, Interdisciplinary, Science, Culture and Technology, with an emphasis on Educational Practices aimed at Vocational and Technological Education, with approaches in formal and non-formal spaces and Guidance and Co-orientation in Final Papers Courses (TCC) and Master's Dissertations. Working in the area of ​​Distance Education, Diversity and Inclusion of Rural Education. He has authored books in the areas of Education, Chemistry and Food Technology. Reviewer for journals: Revista de Educação, Tecnologia e Cultura (ETC), Revista Ciência, Tecnologia e Humanidades (CIENTEC), Revista Práxis (PRÁXIS), Revista Brasileira de Informática na Educação (RBIE), Acta Tecnológica (ACTA), Revista Cubana of Medicinal Plants (RCPM) and Engineering in Agriculture (REVENG). He is currently part of the Permanent Faculty of the Professional Master's Degree in Professional and Technological Education (ProfEPT) offered in the National Network of the Federal Institute of Education, Science and Technology of Maranhão (IFMA).

Oswaldo Palma Lopes Sobrinho, Federal Institute of Education, Science and Technology of Goiás, Campus Rio Verde, Goiás, GO, Brazil

Master's student in Agricultural Sciences - Agronomy with an area of ​​concentration in Sustainable Plant Production in the Cerrado and the Research Line in Sustainable Technologies in Production Systems and Use of Soil and Water by the Federal Institute of Education, Science and Technology of Goiás - Campus Rio Verde (IF Goiano) (Concept 5 by CAPES). Specializing in Sanitation and Rural Environmental Health (SanRural) at the Federal University of Goiás (UFG). Agronomist and Technician in Agriculture at the Federal Institute of Education, Science and Technology of Maranhão (IFMA). Member of the Research Group registered at the National Council for Scientific and Technological Development (CNPq) in Food, Chemistry, Agronomy and Water Resources (AQARH). Journal Reviewer: International Journal of Environment and Waste Management (IJEWM), Engenharia na Agricultura (REVENG), Revista Mundi Engenharia, Tecnologia e Gestão (RMETG), Revista Verde de Agroecologia e Desenvolvimento Sustentável (RVADS), Magazine in Agribusiness and Environment (RAMA), Brazilian Journal of Biosystem Engineering (BIOENG), Brazilian Journal of Irrigation and Drainage (IRRIGA), Brazilian Horticultura (HB) and Acta Tecnológica (ACTA). Member of the Advisory Board of Revista PUBVET and of the Editorial Board of Revista Agrária Acadêmico (RAA). Monitor of the Irrigation and Drainage discipline in the Technical Course in Agriculture at the Federal Institute of Education, Science and Technology of Goiás - Campus Rio Verde (IF Goiano). He develops research in the areas of Agricultural Sciences, with an emphasis on Water and Soil Engineering, Agrometeorology, Soil Science, Phytotechnics, Food Science, in addition to Environmental Sciences.

Layane Bastos dos Santos, Federal Institute of Education, Science and Technology of Maranhão, MA, Brazil

Master's student and fellow in Vocational and Technological Education (EPT) in the National Network, with an area of ​​concentration in Teaching, Line of Research in Educational Practices in EPT and Macro-project in Methodological Proposals and Didactic Resources in formal and non-formal teaching spaces at EPT by the Instituto Federal Institute of Education, Science and Technology of Maranhão (IFMA) - Campus São Luís/Monte Castelo. Member of the Research Group registered at the National Council for Scientific and Technological Development (CNPq) in Food, Chemistry, Agronomy and Water Resources (AQARH). Researcher and teacher in Psychology; Technologist in Advertising at the Federal Institute of Piauí-IFPI. Specialist in People Management, in Educational and School Management and in Psychology and Health, MBA in Marketing and Human Resources. She worked as a professor at the State University of Maranhão in the courses of Business Administration, Full Degree in Portuguese and English Languages ​​and Full Degree in History. He also taught lato sensu postgraduate courses in Teaching in Higher Education, Digital Marketing, Obstetric Nursing, People Management, Intensive Care, Occupational Health, Family Health and Psychopedagogy

Francisco Adelton Alves Ribeiro, Federal Institute of Education, Science and Technology of Maranhão, Campus Codó, Maranhão, MA, Brazil

Doctor in Biotechnology (RENORBIO/UFPI). Master's in Computer and Systems Engineering (UEMA), Specialist in Computer Networks (FSA) and Higher Education Teaching (FACID). Currently, he is a full professor at the Federal Institute of Education, Science and Technology of Maranhão - IFMA. Member of the IFMA Research Groups: Food, Chemistry, Agronomy and Water Resources (AQARH) and the Center for Innovation, Teaching, Research and Extension in Mathematics. Ad hoc consultant (FAPEMA/PATRONAGE). It is part of the permanent faculty of the Professional Master's in Vocational and Technological Education offered on the national network of the IFMA, the SETEC-MEC Assessors Bank, the Recognition of Knowledge and Competencies (RSC) and the IFMA Institutional Scientific Committee. He has experience in Exact and Earth and Interdisciplinary Sciences, with emphasis on Technological Education and Course Completion Work (TCC) Guidance. Advisor and member of Initiation and Research projects: PIBIC Higher and High School, PIBITI High School, in addition to coordinating Institutional Project. Member of the IFMA Institutional Scientific Committee. Consultant for Distance Learning platforms: Blackboard and Moodle, in Educational and Corporate Institutions. He has experience in Education and Technology, Computational Intelligence, Image Processing and Machine Learning. Author of a Computer Program, registered at the National Institute of Intellectual Property (INPI), Assistant Local Coordinator PRONATEC/MEDIOTEC, Campus Codó.

References

AJAY, M. et al. Mechanisms of the anti-hypertensive effect of Roselle L. calyces. Journal of Ethnopharmacology, [S.l.], v. 109, n. 3, p. 388-393, 2007.

ALARCÓN-ALONSO, J. et al. Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract. Journal of Ethnopharmacology, [S.l.], v. 139, n. 1, 751-756, 2012.

ALI, B. H.; WABEL, N. A.; BLUNDEN, G. Phytochemical, Pharmacological and Toxicological Aspects of Hibiscus sabdariffa L.: A review. Phytotheraphy Research, [S.l.], v. 19, p. 369-375, 2005.

ALI, B. H. et al. Effect of aqueous extract of anthocyanins and calyces of Roselle (Malvaceae) in rats with adenine-induced chronic kidney disease. Journal of Pharmacy and Pharmacology, [S.l.], v. 69, n. 9, p. 1.219-1.229, 2017.

ALI, M. B. et al. Investigation of the potential of Roselle calyces. Journal of Ethnopharmacoly, [S.l.], v. 31, n. 2, p. 249-257, 1991.

AL-MAMUN, A. et al. In vitroevaluation of the antibacterial, cytotoxic and insecticidal activities of Hibiscus sabdariffafruits. Libyan Agriculture Research Center Journal Internation, [S.l.], v. 3, n. 1, 144-149, 2011.

AL-MAMUN et al. In vitro Evaluation of the Antibacterial, Cytotoxic and Insecticidal Activities of Hibiscus sabdariffa Fruits. Libyan Agriculture Research Center Journal Internation, [S.l.], v. 2, n. 3, p. 144-149, 2011.

CARDOSO, M. O. Vegetables unconventional Amazon. Brasília, DF: Embrapa-SPI. 1997.

CORADIN, L.; SIMINSKI, A.; REIS, A. Native species of flora of current or potential economic value: plans for the future. Brasília, DF: South Region Brasilia. 2011.

EZZAT, S. M. et al. Metabollic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces. Pharmaceutical Biology, [S.l.], v. 54, n. 12, p. 3.172-3.181, 2016.

FULLERTON, M. S. C. et al. Determination of antioxidant contents in red sorrel and its anticarcinogenic potential in azoxymethane-induced colonic aberrant crypt foci. Research Journal of Phytochemistry, [S.l.], v. 2, n.1, p. 69-76, 2008.

GALVÃO, M. C. B. The bibliographic and scientific research. epidemiology fundamentals. 2018. 2nd ed. The 398, 1-377. Available at: http://www2.eerp.usp.br/Nepien/DisponibilizarArquivos/Levantamento_bibliografico_CristianeGalv.pdf. Access: 15 Feb. 2019.

GOMES, F. Understand the importance of patents for the creative industry. 2018. Available at: http://fgmarcas.com.br/entenda-a-importancia-das-patentes-para-a-industria-criativa-2/. Access: 10 Mar. 2019.

GURROLA-DIÁZ, C. M. et al. Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy). Phytomedicine, [S.l.], v. 17, n. 1, p. 500-505, 2010.

HERRERA-ARELLANO, A. et al. 2007. Clinical effects produced by the standardized herbal medicinal product of Roselle on Patients with hypertension. A randomized, double-blind, Lisinopril-controlled clinical trial. Planta Medica, [S.l.], v. 73, p. 6-12, 2007.

HIRUNPANICH, V. et al. Antioxidant effects of aqueous extracts from dried calyx of Hibiscus sabdariffa Linn. (Roselle) in vitro using rat low-density lipoprotein (LDL). Biological & Pharmaceutical Bulletin, [S.l.], v. 28, n. 3, p. 481-484, 2005.

INPI – INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL. Patent Classification. 2018. Available at: http://www.inpi.gov.br/menu-servicos/patente/classificacao-de-patentes. Access: 11 Feb. 2019.

INUWA, I. et al. Longterm ingestion of Roselle calyx extract Enhances myocardial capillarization spontaneously hypertensive rat in the. Experimental Biology and Medicine, (Maywood), v. 237, n. 5, p. 563-569, 2012.

ISMAIL, A.; IKRAM, E. H. K; NAZRI, H. S. M. Roselle (Hibiscus sabdariffa L.) seeds nutritional composition protein quality and health benefits. Food, [S.l.], v. 2, n. 1, p. 1-16, 2008.

KAO, E. S. et al. Polyphenolic extract from Hibiscus sabdariffa reduces body fat by inhibiting hepatic lipogenesis and preadipocyte adipogenesis. Food Funct, [S.l.], v. 7, n. 1, p. 171-182. DOI: 10.1039/c5fo00714c.

KAPEPULA, P. M.1. Comparison of bioactivities and metabolic profiles of the leaves of three Congolese Hibiscus edible species. Natural Product Research, [S.l.], v. 31, n. 24, p. 2.885-2.892, 2017.

LEWINSOHON, T. M.; PRADO, P. I. Brazilian Biodiversity: Current State of Knowledge Synthesis. 2018. Available at: http://www.mma.gov.br/port/sbf/chm/doc/estarte.doc. Access: 2 Mar. 2018.

LIN, T. et al. Hibiscus sabdariffa extract angiograms serum cholesterol in men and women. Nutrition Research, [S.l.], v. 27, n. 3, p. 140-145, 2007.

LIU, J. Y. et al. The protective effects of Hibiscus sabdariffa extract on CCl4-induced liver Brosis in rats. Food and Chemical Toxicology, [S.l.], v. 44, p. 336-343, 2006.

LORENZI, H.; MATOS, F. J. A. Medicinal Plants in Brazil, Native and Exotic. Plantarum Institute of Plant Studies LTDA. São Paulo, 2002.

MOHAMMED, A. et al. Roselle (Hibiscus sabdariffa) seed oil is a rich source of (-) tocopherol. Journal of Food Science, [S.l.], v. 72, p. 207-211, 2007.

MOHD-ESA, N. et al. Indifferent parts Antioxidant activity of roselle (Hibiscus sabdariffa L.) extracts and exploitation potential of the seeds. Food Chemistry, [S.l.], v. 122, n. 4, 1.055-1.060, 2010.

MORTON, J. F. Roselle. In: Fruits of warm climates. Miami, USA: Florida Flair Books, 1987. p 2.081-2086.

OLALEYE, M. T. Cytotoxicity and antibacterial activity of Methanolic extract of Hibiscus sabdariffa. Journal of Medicinal Plants Research, [S.l.], v. 1, n. 1, p. 9-13, 2007.

OLALYE, M. T.; ROCK, J. B. Commonly used medicinal plants tropical exhibit distinct in vitro antioxidant activities against hepatotoxins in rat liver. Experimental and Toxicologic Pathology, [S.l.], v. 58, n. 6, 433-438, 2007.

PAIM, M. P. et al. Anti-Escherichia coli effect of Roselle L. In the meat model. Food Science and Technology, [S.l.], v. 37, v. 4, p. 647-650, 2017.

SARR, M. et al. In vitro vasorelaxation mechanisms of bioactive compounds extracted from Roselle on rat thoracic aorta. Nutrition & Metabolism, [S.l.], v. 6, n. 45, p. 1-12, 2009.

Downloads

Published

2019-12-28

How to Cite

Cavalcante, K. C., Pinheiro, G. D., Pereira, Álvaro I. S., Lopes Sobrinho, O. P., Santos, L. B. dos, & Ribeiro, F. A. A. (2019). Potencialidades Farmacológicas da Espécie Vinagreira: um estudo realizado por meio das técnicas de prospecção científica e tecnológica. Cadernos De Prospecção, 12(4), 920. https://doi.org/10.9771/cp.v12i4.32490

Issue

Vol. 12 No. 4 (2019)

Section

Prospecções Tecnológicas de Assuntos Específicos

License

Copyright (c) 2019 Cadernos de Prospecção

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

O autor declara que: - Todos os autores foram nomeados. - Está submetendo o manuscrito com o consentimento dos outros autores. - Caso o trabalho submetido tiver sido contratado por algum empregador, tem o consentimento do referido empregador. - Os autores estão cientes de que é condição de publicação que os manuscritos submetidos a esta revista não tenham sido publicados anteriormente e não sejam submetidos ou publicados simultaneamente em outro periódico sem prévia autorização do Conselho Editorial. - Os autores concordam que o seu artigo ou parte dele possa ser distribuído e/ou reproduzido por qualquer forma, incluindo traduções, desde que sejam citados de modo completo esta revista e os autores do manuscrito. - Revista Cadernos de Prospecção está licenciado com uma Licença Creative Commons Attribution 4.0. Esta licença permite que outros remixem, adaptem e criem a partir do seu trabalho para fins não comerciais, e embora os novos trabalhos tenham de lhe atribuir o devido crédito e não possam ser usados para fins comerciais, os usuários não têm de licenciar esses trabalhos derivados sob os mesmos termos. Licença Creative Commons
Este obra está licenciado com uma Licença Creative Commons Atribuição 4.0 Internacional.