Technological Prospection and Neuropathic Pain: therapeutic perspective

Authors

DOI:

https://doi.org/10.9771/cp.v11i5.26985

Keywords:

Neuropathic pain, Pain, Technological prospecting.

Abstract

The objective of this contribution is to present a possible future scenario of the market for development and production of pain medications. The state of the treatment and management of neuropathic pain from the point of view of pharmaceutical technological development and health technologies is analyzed through research in a database of patents and clinical trials in progress. For this, studies of technological prospection were made during the period of 11 years, between the years 2006 to 2017.The results of the research were satisfactory, concluding that the technology is more widely used in countries of North America, Europe and Asia, where investments and drug research development are greater. Thus, it is possible to verify that the USA is the largest depository of patents and scientific articles, with a significant number of anti-inflammatory and analgesic development, as well as antidepressants, widely used in treatment. Brazil has seen growth over the years, but still has a small number of patents.

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Author Biographies

Keicyane Aguiar da Silva, University of Brasilia, Brasilia, DF, Brazil

Undergraduate student in Pharmacy at the Faculty of Ceilândia, University of Brasília

Mani Indiana Funez, University of Brasilia, Brasilia, DF, Brazil

Bachelor in Nursing and Licentiate from the Federal University of Paraná (2001), Master's (2004) and Doctorate (2008) in Sciences from the Pharmacology Department of the Faculty of Medicine of Ribeirão Preto - University of São Paulo. He completed a post-doctoral internship at the Pathophysiology Laboratory of the Butantan Institute (2009). Has experience in Pharmacology, with emphasis on Pharmacology of Pain, working mainly on the following topics: pain chronification mechanisms, cell signaling, opioids, pain and analgesia. It also works in the area of ​​pain and analgesia in adult health. At graduation, she works in the areas of Adult and Elderly Health Nursing, with an emphasis on Medical-Surgical Nursing and Pharmacology. Member of the Brazilian Society of Experimental Pharmacology and Therapeutics, of the International Association for the Study of Pain and of the Brazilian Nursing Association.

Paulo Gustavo Barboni Dantas Nascimento, University of Brasilia, Brasilia, DF, Brazil

He holds a Bachelor's degree in Chemistry from the University of São Paulo (1998), a Master's degree in Chemistry from the FFCLRP, University of São Paulo (2001), a PhD in Chemistry from the FCFRP, from the University of São Paulo (2005) and a postdoctoral degree in Pharmacology , in the FMRP (2009). Has experience in Chemistry, with emphasis on drug development, working mainly on the following topics: computational chemistry, spectroscopic methods, SAR and QSAR, phytochemistry, pathophysiology of pain, experimentation in in vivo inflammatory pain models, development of analgesics. He is currently an adjunct professor at the University of Brasília of the disciplines of Physical Chemistry Applied to Pharmacy and Physical-Chemical Quality Control at the Faculty of Ceilândia in the undergraduate course in Pharmacy. Lato sensu specialist in Technologies in Learning, at Centro Universitário Senac (2016). Senior Editor of Periodical Dor on line (www.dol.inf.br). Professor responsible for the discipline of Technological Prospecting at the UnB/CDT focal point of the Professional Master's Degree in Intellectual Property and Technology Transfer for Innovation - ProfNIT

References

AKKARI, A. C. S. et al. Inovação tecnológica na indústria farmacêutica: diferenças entre Europa, os EUA e os países farma-emergentes. Guest. Prod., São Carlos, v. 23, n. 2, p. 365–380, 2016.

ASSOCIAÇÃO DA INDÚSTRIA FARMACÊUTICA DE PESQUISA (Interfarma). Guia Interfarma. 2016. Disponível em: <https://www.interfarma.org.br/guia>. Acesso em: 30 abr. 2018.

CUNHA, T. M. et al. Dor inflamatória Tratado de dor. Publicação da sociedade brasileira para estudo da dor. 1. ed., vol. 1. Rio de janeiro: Atheneu, 2017. p. 283–299.

FERREIRA, S. H, et al. Dor inflamatória. Dor, princípios e prática. vol. 1. Porto Alegre: Artmed, 2008. p. 268–279.

INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL (INPI). Base de dados on-line. [2018]. Disponível em: <https://gru.inpi.gov.br/pePI/jsp/patentes/PatenteSearchBasico.jsp>. Acesso em: 15 jan. 2019.

MAYERHOFF, Z. D. V. L. Uma análise sobre os estudos de prospecção tecnológica. Rio de Janeiro: INPI. 2008.

ORBIT INTELLIGENCE. Base de dados on-line. [2018]. Disponível em: <https://www.orbit.com>. Acesso em: 15 jan. 2019.

PERRETTI, Mauro et al. Resolution Pharmacology: Opportunities for therapeutic innovation in inflammation. Trends Pharmacological Sciences, London, v. 36, n. 11, p. 737–755, nov. 2015.

SISIGNAMO, M.; PARNHAM, M. J.; GEISSLINGER, G. Drug repurposing for the developement of novel analgesics. Trends Pharmacological Sciences, Frankfurt, Germany, v. 37, n. 3, p.172–183, mar. 2015.

TIBBS, G. R.; POSSON, D. J.; GOLDSTEIN, P. A. Voltage-gated ion channels in the pns: novel therapies for neuropathic pain? Trends in Pharmacological Sciences, New York, v. 37, n. 7, p. 522–542, jul. 2016.

WORLD INTELLECTUAL PROPERTY ORGANIZATION (WIPO). PATENTSCOPE: base de dados on-line. [2018]. Disponível em: <https://patentscope.wipo.int/search/pt/search.jsf>. Acesso em: 15 jan. 2019.

Published

2018-12-10

How to Cite

Silva, K. A. da, Funez, M. I., & Nascimento, P. G. B. D. (2018). Technological Prospection and Neuropathic Pain: therapeutic perspective. Cadernos De Prospecção, 11(5), 1491. https://doi.org/10.9771/cp.v11i5.26985