Technological assessment of Biological Activity and Technological Processes using Baccharis Genus Based on Patent applications

Authors

DOI:

https://doi.org/10.9771/cp.v11i2.23357

Keywords:

Baccharis, Baccharis activity, Baccharis products.

Abstract

Prospective studies aim to identify knowledge and technologies applied in the health sector, through the treatment of diseases with the use of medicinal plants, highlighting in this research the plants of the genus Baccharis. This plant genus contains several bioactive compounds with therapeutic actions important for the promotion of human health. However, the article presented a mapping of deposited patents that use the genus Baccharis as a beneficial agent for health. The patents were searched in the following databases: INPI, LATIPAT and Espacenet, using the descriptors: Baccharis, Baccharis activity, and Baccharis products. Were found 67 patents and 19 of them were selected for the study. It has been found that the number of patents found is relatively low and the highest number of patents is classified as A61K, noting that the greatest potential of the plant is used for the production of products related to medical science and hygiene. 

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Author Biographies

Nilane Françoise Patel, State University of the Midwest, Garapuava, PR, Brazil.

Master's student in Pharmaceutical Sciences at the State University of the Midwest. Graduated in Biomedicine from Faculdade Campo Real. Assists in the coordination of a specific project financed by SETI.

Andressa Razera Pezoti, State University of the Midwest, Garapuava, PR, Brazil.

Master's student in Pharmaceutical Sciences at the State University of the Midwest (UNICENTRO). Graduated in Veterinary and Pharmacy from UNICENTRO.

Daniel Zanardini Fernandes, State University of the Midwest, Garapuava, PR, Brazil.

Undergraduate student in Physical Education at the State University of the Midwest.

Carlos Ricardo Maneck Malfatti, State University of the Midwest, Garapuava, PR, Brazil.

Graduated in Biomedicine and Physical Education, Adjunct Professor at Universidade Estadual do Centro Oeste (PR), Coordinator of the Professional Master's Degree in Intellectual Property - PROFNIT - UNICENTRO, permanent member of the Doctorate in Chemistry, Master's and Doctorate in Pharmaceutical Sciences and in the Professional Master's Degree in PROFNIT NATIONAL NETWORK. He holds a Post-Doctorate in Chemical and Biochemical Process Technology - UTFPR (2014), a PhD in Biological Sciences: Biochemistry - UFRGS (2007) and a Master's in Biological Sciences: Biochemistry - UFSM (2001).

Claudia Crisostimo, State University of the Midwest, Garapuava, PR, Brazil.

Master in Law from the Federal University of Paraná, UFPR. Doctoral student in Public Law at the Faculty of Law of the University of Coimbra, Portugal, developing thesis on Intellectual Property Rights. Graduated in Law from Faculdade Novo Ateneu de Guarapuava. Director of the Intellectual Property Division at Unicentro's Technological Innovation Agency, NOVATEC. Lawyer at the Universidade Estadual do Centro Oeste do Paraná, Unicentro, OAB/PR 53724. Researcher in the following areas: Intellectual Property Rights (Copyright and Industrial Law - Trademarks and Patents), Administrative Law, Philosophy of Law, Environmental Law and Theory of Law. Leader of the Research Group: Innovation Management and Intellectual Property. Member of the Research Group: Politics, Citizenship and Modernity.

Vanusa Karini Savighago, State University of the Midwest, Garapuava, PR, Brazil.

Degree in Biomedicine from Faculdade Campo Real (2014). Specialization in Aesthetic Biomedicine by NEPUGA (2016) Postgraduate student in Biomedical Sciences - UNICENTRO- PR Graduate student of Nutrition - Faculdade Campo Real Professor of the collegiate of Aesthetics and Cosmetics at the Faculty of Guairacá Biomédica Esteta at the company Donnadon Beleza e Bem Estar- Guarapuava- PR Biomédica Esthete at Espaço Bem Viver - Francisco Beltrão-PR

References

BAGGIO, C. H. et al. Gastroprotective effects of a crude extract of Baccharis illinita DC in rats. Pharmacological Research, [S.l.], v. 47, n. 1, p. 93–98, 2003.

BASTOS, J. K.; FURTADO, N. A. J. C. Processo de obtenção de extratos padronizados, frações e substáncias isoladas de própolis ou espécies de Baccharis, formulações de extratos padronizados, frações e substáncias isoladas de própolis ou espécies de Baccharis, e o uso de formulações de extratos padronizados, frações e substáncias isoladas de própolis ou espécies de Baccharis como sanitizantes, anti-sépticos e/ou desinfetantes. BR Pat. PI 0800363-7 A2. 2008.

BOLLER, S. et al. Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation. Journal of ethnopharmacology, [S.l.], v. 130, n. 2, p. 262–266, 2010.

CAMPOS, F. R. et al. Atividade antiúlcera de extratos, frações e compostos isolados, processo de obtenção e uso da espécie Baccharis glaziovii baker (Asteraceae). BR Pat. BR 10 2015 024304 9 A2. 2015.

CANALLI, W. M.; SILVA, R. P. Uma breve história das patentes: Analogias entre ciência/ tecnologia e Trabalho intelectual / trabalho Operacional. In: SCIENTIARUM HISTORIA Lv, 2011, Rio de Janeiro. Congresso Scientiarum Historia Lv. Rio de Janeiro: UFRJ, 2011. v. único. p. 742–748.

CARREIRAS, J. A. G. Combination of vegetable (particularly thistle) extracts modifies immune response and is effective against e.g. multiple sclerosis. ES Pat. ES2156694 A1. 2001.

CARRERA, R. C. Baccharis trimera (Less.) DC. (Asteraceae): estudo comparativo dos óleos voláteis, atividade biológica e crescimento de estacas de populações ocorrentes em áreas do Cerrado e Mata Atlântica. 191 f. Tese (Doutorado) – Programa de Pós-graduação em Biodiversidade Vegetal e Meio Ambiente. Instituto de Botânica da Secretaria do Meio Ambiente, São Paulo 2007.

CORRIE, M. Therapeutic compositions. GB Pat. GB1281526 A. 1972.

DAILEY, G. R.; JARVIS, B. N.; KUPCHAN, M. S. Anti-leukemic trichothecene epoxides. US Pat. US4164584 A. 1979.

EMERENCIANO, V. P. et al. Flavonoids as chemotaxonomic markers for Asteraceae. Biochemical Systematics and Ecology, v. 29, p. 947–957, 2001.

FABIANE, K. C. et al. Physicochemical characteristics oh the essesntial oils of Baccharis dracunculifolia and Baccharis uncinella DC. (Asteraceae). Brazilian Journal of Pharmacognosy, [S.l.], v. 18, n. 2, p. 197–203, abr./jun. 2008.

FABRI, R. L. Et al. Potencial antioxidante e antimicrobiano de espécies da família Asteraceae. Rev. Bras. PI. Med., Botucatu, v. 13, n. 2, p. 183–189, 2011.

BENPU FENGNAIBAO HEALTH FOOD CO LTD. Baccharis dracunculifolia DC. propolis and seabuckthorn soft capsule and preparation method thereof. CN Pat. CN105410921. 2015.

FERRONATTO, R. et al. Atividade antioxidante dos óleos essenciais produzidos por Baccharis dracunculifolia D.C. e Baccharis uncinella D.C. (Asteraceae). Arquivos de Ciências da Saúde, Umuarama, v. 10, n. 2, p. 67–70, 2006.

FREITAS, J. C. Complemento alimentar para auxiliar no tratamento e controle de diabetes. BR Pat. BRPI0401061 A. 2005.

GELINSKI, J. M. L. N. et al. Atividade antibacteriana do óleo essencial de Baccharis dracunculifolia D.C. e de seu composto ativo nerolidol em combinação ao EDTA ou lisozima. Evidênica, [S.l.], v. 7, n. 2, p. 131–144, 2007.

JARVIS, B. B. et al. Trichotecenos mycoto-xins from Brazilian Baccharis species. Phytochemistry, [S.l.], v. 30, p. 789–797, 1991.

KALLUF, L. J. H. Fitoterapia funcional: dos princípios ativos à prescrição de fitoterápicos. 1. ed. São Paulo: VP Editora, 2008.

KOMAZAKI, H. et al. M. Skin external preparation. JPH Pat. JPH0812565 A. 1997.

KUPFER, D.; TIGRE, P. Prospecção Tecnológica. In: CARUSO, L. A.; TIGRE, P. B. (Org.). Modelo SENAI de prospecção: documento metodológico. Montevideo: OIT/CINTERFOR, 2004.

LEMOS, M. et al. Baccharis dracunculifolia, the main botanical source of Brazilian green propolis, displays antiulcer activity. Journal of Pharmacy and Pharmacology, Ribeirão Preto, v. 59, p. 603–608, 2006.

LLANO, A. MANUEL, A. Agente que muestra acción antitumoral en el cuadro sanguíneo y regulador del medio interno. AR Pat. AR053785 A1. 2007.

LOPEZ, F. V. et al. Óleos essenciais e compostos isolados de extratos de Baccharis spp., formulações farmacêuticas e/ou cosméticas e seus usos. BR Pat. PI 0900802-0 A2. 2009. 27p.

MALFATTI, C. R. M.; PEREIRA, R. A. Processo de extração e uso de Baccharis dracunculifolia para amplificar a secreção de insulina in vivo. BR Pat. BR 10 2012 020540 8 A2. 2012..

MIGUEL, O. G.; MIGUEL, M. D.; FOLQUITTO, D. G. Método de extração e uso do óleo essencial, extrato e frações com atividade antitumoral, antioxidante e antimicrobiana das partes aéreas e raiz de Baccharis milleflora (less.) dc., asteraceae. BR Pat. BR 10 2014 031505 5 A2. 2014.

NAKASUGI, T. Antimutagenic agent. JPH Pat. JPH11180867 A. 1999.

OLIVEIRA, A. C. P. et al. Effect of the extracts and fractions of Baccharis trimera and Syzygium cumini on glycaemia of diabetic and non-diabetic mice. Journal of ethnopharmacology, [S.l.], v. 102, n. 3, p. 465–469, 2005.

OLIVEIRA, L. G. et al. Informação de Patentes: ferramenta indispensável para a pesquisa e o desenvolvimento tecnológico. Química nova, Brasília (DF), v. 28, suplemento, S36–S40, 2009.

PEREIRA, R. A. Efeitos do tratamento do extrato metanólico de Baccharis dracunculifolia sobre alterações bioquímicas e histológicas de um modelo animal de diabetes. 2012. 69 f. Dissertação (Mestrado em Ciências Farmacêuticas) – Universidade Estadual do Centro-Oeste. Guarapuava, 2014.

PEREIRA, R. S. Uso de extrato seco de Baccharis trimera para reverter sintomas de obstipação intestinal. BR Pat. PI 0701121-0 A8. 2007.

SANCHEZ, J. L. A. Composicion herbal para el tratamiento de psoriasis. MX Pat. MX2007010360 A. 2009.

______. Formulation based on an extract of medicinal plants, coal tar pitch and salicylic acid for the effective control of psoriasis, method for obtaining said extract and forms of administration of the formulation. WO Pat. WO2013015665. 2013.

SANTOS, C. D.; SOUZA, S. P. Ação inibitória de extratos de plantas sobre lipase pancreática. BR Pat. BRPI0914283 A2. 2012.

SHIBATA, I. et al. Material for medicament or health food and method for producing the same. JP Pat. JP2001245629 A. 2001.

TREVISAN, M. M. W.; FABIANE, K. C.; ONOFRE, S. B. Abordagem fitoquímica de Baccharis dracunculifolia (Asteraceae). Revista de Biologia e Saúde da UNISEP, (online), v. 2, n. 1, 2008.

VERDI, L. G.; BRIGHENTI, I. M. C.; PIZZOLATTI, M. G. Gênero Baccharis (Asteraceae): aspectos químicos, econômicos e biológicos. Química Nova, Brasília (DF), v. 28, n. 1m p. 85–94, 2005.

VIDARI, G. P. et al. 2003. Antiulcer and antidiarrhoeic effect of Baccharis teindalensis. Pharmaceutica Biology, [S.l.], v. 41, p. 405–411, 2003.

Published

2018-09-30

How to Cite

Patel, N. F., Pezoti, A. R., Fernandes, D. Z., Malfatti, C. R. M., Crisostimo, C., & Savighago, V. K. (2018). Technological assessment of Biological Activity and Technological Processes using Baccharis Genus Based on Patent applications. Cadernos De Prospecção, 11(2), 628. https://doi.org/10.9771/cp.v11i2.23357

Issue

Section

Prospecções Tecnológicas de Assuntos Específicos