Interrelationship between periodontal disease and Crohn’s disease

Authors

  • Fernanda Brito
  • Roberta Rocha Pedreira
  • Ricardo Guimarães Fischer
  • Carlos Marcelo da Silva Figueredo

DOI:

https://doi.org/10.9771/cmbio.v5i3.4134

Keywords:

Periodontal disease- Crohn‘s disease - T cells profile.

Abstract

The aim of this review was to assess the possible relationship between periodontal disease and Crohn‘s disease. The tissue destruction in periodontitis, a specific host reaction against the local accumulation of bacteria, is determined by the nature and the balance of celular and humoral immune responses. Theories have been postulated to explain the progression of gingivitis to periodontitis in the context of the Th1/Th2 paradigm. Crohn‘s disease has a Th1 profile and a number of inflammatory mediators are present in the inflamed intestinal mucosa. In conclusion, it is possible periodontitis is more prevalent in patients with Crohn‘s disease because these two diseases share pathogenic pathways, probably, due to the same T cells profile.

Downloads

Download data is not yet available.

Downloads

Published

2006-07-01

How to Cite

Brito, F., Pedreira, R. R., Fischer, R. G., & Figueredo, C. M. da S. (2006). Interrelationship between periodontal disease and Crohn’s disease. Journal of Medical and Biological Sciences, 5(3), 261–267. https://doi.org/10.9771/cmbio.v5i3.4134

Issue

Vol. 5 No. 3 (2006): Revista de Ciências Médicas e Biológicas

Section

Review Articles

License 

The Journal of Medical and Biological Sciences reserves all copyrights of published works, including translations, allowing, however, their subsequent reproduction as transcription, with proper citation of source, through the Creative Commons license. The periodical has free and free access.

Most read articles by the same author(s)