EFFECTS OF HIBISCUS SABDARIFFA L. TEA INTAKE ON ANTIOXIDANT RESPONSE AND BIOCHEMICAL PROFILE IN HEALTHY WISTAR RATS

EFEITOS DO CONSUMO DO CHÁ DE HIBISCUS SABDARIFFA L. SOBRE A RESPOSTA ANTIOXIDANTE E PERFIL BIOQUÍMICO EM RATAS WISTAR SAUDÁVEIS

Authors

  • Alana Louzada Millions Monteiro Nutritionist, Postgraduate Program in Nutrition Sciences, Fluminense Federal University, Niterói https://orcid.org/0000-0001-7370-8040
  • Lumena Isis de Oliveira Santos Nutritionist, Postgraduate Program in Nutrition Sciences, Fluminense Federal University, Niterói
  • Vanessa Rosse de Souza Nutritionist, Functional Foods Laboratory, Federal University of Rio de Janeiro State, Rio de Janeiro
  • Vilma Blondet de Azeredo Nutritionist, PhD in Food Science, Professor of Nutrition and Dietetic Department, Fluminense Federal University, Niteroi
  • Anderson Junger Teodoro Nutritionist, PhD in Food Science, Professor of Nutrition and Dietetics Department, Fluminense Federal University, Niteroi https://orcid.org/0000-0002-0949-9528
  • Mariana Sarto Figueiredo Nutritionist, PhD in Science, Professor of Nutrition and Dietetics Department, Fluminense Federal University, Niteroi https://orcid.org/0000-0002-8539-3063

DOI:

https://doi.org/10.9771/cmbio.v22i4.52474

Keywords:

Hibiscus Sabdariffa; Antioxidants; Functional foods; Diabetes.

Abstract

Introduction: Hibiscus Sabdariffa L. have therapeutic potential characteristics, rich in phytochemicals with anti-inflamatory, antibacterial and antioxidant effects. Objective: The study aims to evaluate daily consumption of hibiscus tea, in a concentration usually consumed by population, on biochemical parameters and antioxidant activity in healthy female adult Wistar rats. Methodology: The animals were divide in Control Group (CG), which received filtered water and commercial diet; and Hibiscus Group (HG), which received 15 mL/day of Hibiscus Sabdariffa L. flower tea (prepared 1g of flower/100mL of water), commercial diet and filtered water. The infusion of hibiscus flower for tea preparation was performed daily (ratio of 1.0g of dried flower to 100 mL of filtered boiled water), infused for 10 minutes, strained, and daily offered to animals (15 mL/day/animal) during 84 days. After 84 days of experimental protocol, animals were euthanized and evaluated serum biochemical parameters such urea, creatinine, calcium, magnesium, phosphorus, iron, total proteins, albumin, lipid profile and fasting glycemia. Analysis of antioxidant components was perfomed on hibiscus tea and serum antioxidant activity data were also analyzed by 2,2-difenil-1-picrylhydrazyl (DPPH), Oxygen Radical Absorbance Capacity (ORAC) and total antioxidant activity by iron reduction (FRAP) methods. Results: Hibiscus tea has a high antioxidant potential, and reduce fasting glucose (p < 0.05), but in concentration offered this antioxidant capacity was not observed at serum level, without changes on body mass, water intake, food consumption, lipid profile, liver and kidney biomarkers. Conclusion: Hibiscus tea daily consumption, showed higher antioxidant potential and reduce fasting blood glucose, without toxic effects.

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Published

2023-12-22

How to Cite

Monteiro, A. L. M. ., Santos, L. I. de O., Souza, V. R. de ., Azeredo, V. B. de, Teodoro, A. J. ., & Figueiredo, M. S. . (2023). EFFECTS OF HIBISCUS SABDARIFFA L. TEA INTAKE ON ANTIOXIDANT RESPONSE AND BIOCHEMICAL PROFILE IN HEALTHY WISTAR RATS: EFEITOS DO CONSUMO DO CHÁ DE HIBISCUS SABDARIFFA L. SOBRE A RESPOSTA ANTIOXIDANTE E PERFIL BIOQUÍMICO EM RATAS WISTAR SAUDÁVEIS . Journal of Medical and Biological Sciences, 22(4), 605–614. https://doi.org/10.9771/cmbio.v22i4.52474

Issue

Vol. 22 No. 4 (2023): Revista de Ciências Médicas e Biológicas

Section

ORIGINAL ARTICLES

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