The profile of breast cancer in Salvador: prognostic factors of invasive ductal carcinoma in Salvador, Bahia

fatores prognósticos do carcinoma ductal invasivo

Abstract

Abstract

Introduction: breast cancer is a challenge for science, considering the variety of prognostic factors and its importance for the disease’s treatment. Objective: this work is a descriptive retrospective observational study that sought to describe the prognostic factors of breast cancer in patients from Salvador-BA city. Methods: 463 immunohistochemistry samples from Pathological Anatomy Studies Center (CEAP) were selected from December 2016 to December 2018, from which variables were analyzed, such as patient age, histological grade, expression of receptors, presence of HER2, Ki-67 count and histological type. Results: the mean age of the patients was 55 years. Histological grade was assessed as grade 1 in 14.32% of cases, grade 2 in 58.88% and grade 3 in 26.79%. Estrogen receptor expression was observed in 72.62% of cases, progesterone receptor expression in 63.71%, presence of HER2 in 15.33% and Ki-67> 15% in 39.52%. As for the histological type, 49.5% was Luminal A, 20.1% triple negative, 15.3% Luminal B, 8.2% HER2 positive and 6.9% triple positive. Conclusion: these results showed similarities and differences when compared to similar studies conducted inside and outside Brazil.