Association of antibiotics and oral contraceptives

Abstract

The Oral Contraceptives have been more and more prescribed in medical practice for the treatment of several pathologies like dismenorreia and Ovarian Policystics Syndrome (OPS), quite frequent in the women in fertile age. However, the main use of this drug is, undoubtedly, in the prevention of the no wanted pregnancy, through the suppression of the stimulating folicule hormone (SFH) in the ovarian cycle. This hormonal blockade can suffer interference for the concomitant use of other medicines - fact this denominated Drug Interaction. They stand out the Antibiotics, medicines progressively more used in the treatment of infections. The objective of this work is, therefore, to discuss and to explain the mechanisms of occurrence of the Drugs Interaction among Oral Contraceptives and Antibiotic, being pointed out the drugs more involved in the reduction of the contraceptive effect.