Water-soluble polyvinylpyrrolidone-iodine (PVP-I) on concentrations of 0.1% and 0.5% in antisepsis of dogs ophthalmic surgery

Abstract

The objective of this study was to compare the bactericide effect of polyvinylpyrrolidone-iodine at concentrations of 0.1% and 0.5% on antisepsis of dog ophthalmic region. Solutions with different concentrations were used on each eye of twenty dogs. On the right eye, the 0.1% solution was administered and, on the left eye, the 0.5% solution. Conjunctival sampling of both groups was performed before antisepsis (0), after 30 minutes (1), 1.5h (2) and 2.5h (3) of irrigation and cleaning. Bacterial growth was identified in 70% of ocular sample collected before the antisepsis. The bacterial agents found on different times of sampling were Staphylococcus intermedius, Staphylococcus aureus, Staphylococcus sp., Staphylococcus epidermidis, Bacillus sp. Diphtheroids, Enterobacter sp., Micrococcus sp. The 0.1% solution of polyvinylpyrrolidone-iodine decreased by 64% and 50% bacteria growth after 1 and 2, respectively. The group that used the concentration of polyvinylpyrrolidone-iodine 0.5% showed greater bactericide power. Therefore, the solution of polyvinylpyrrolidone-iodine to 0.5% compared to 0.1% solution was more effective in reduction of the conjunctival microbiota up to 90min after antisepsis.